Director, IT Site Lead

Location: Salt Lake City
Posted on: June 23, 2025

Job Description:

Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients. We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients. The Director, IT Site Lead will be the primary IT leader for Denali’s Salt Lake City (SLC) office, serving as an extension of our IT team headquartered in South San Francisco. This key role ensures that the IT infrastructure, applications, and services at the SLC site are fully aligned with our corporate IT strategies. The ideal candidate will bring experience in IT within a biotech manufacturing environment and will oversee all IT operations at the SLC location. Key Accountabilities/Core Job Responsibilities: IT Leadership: Act as the IT lead for the SLC facility, ensuring alignment with the corporate IT strategy and goals. Collaboration: Develop and maintain strong business partnerships with site leadership and stakeholders, ensuring IT initiatives and services are effectively integrated with business objectives. Infrastructure Management: Oversee the implementation, maintenance, and support of IT infrastructure, including networks, servers, storage, and telecommunications at the SLC site. End User Services: Manage end-user support and ensure high levels of customer satisfaction within the SLC facility. Applications Support: Ensure that all applications and systems supporting the manufacturing processes are functioning optimally, including ERP, MES, and other critical systems. Compliance and Security: Ensure compliance with all relevant regulations, including FDA, GMP, and other biotech industry standards. Implement and maintain robust information security protocols. Project Management: Lead and manage IT projects related to the SLC site, including the deployment of new systems and services. Vendor Management: Manage relationships with external IT service providers and vendors, ensuring service level agreements (SLAs) are met. Team Leadership: Lead and develop the IT team at the SLC site, fostering a culture of excellence and continuous improvement. Lead direct report(s) through annual goal setting, growth planning, adherence to company policies, maintain training compliance and provide ongoing feedback on growth, development and areas of improvement. Required Qualifications/Skills: Bachelor’s degree in Information Technology, Computer Science, or a related field. Advanced degree is a plus. 10 years of experience in IT, with at least 8 years in a leadership role within a biotech or pharmaceutical manufacturing environment. Extensive experience with biotech manufacturing IT systems, including ERP, MES, and laboratory systems. Required Qualifications/Skills: Bachelor’s degree in Information Technology, Computer Science, or a related field. Strong understanding of FDA regulations, GMP, and other biotech industry compliance standards. Ability to travel as needed between Salt Lake City and South San Francisco. Advanced degree a plus Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future. Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Keywords: , Draper , Director, IT Site Lead, IT / Software / Systems , Salt Lake City, Utah